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Neuropathfinding: Kinesthetic Model
For brain circuits to function properly, neurons must find and make appropriate connections during development. Once at their destination, axons makes connections with other nerve cells or muscle.
Students model the migration of neuronal axons to find their targets.
Grade Level: 5-12
Lesson Length: 1 class period
Extra Resources
These videos were produced by the Paul Letourneau Lab at the University of Minnesota.
Nerve Growth Cones-narrated version
Nerve Growth Cones-subtitles only
Growth cone guidance by a repulsive substrate
Growth cone guidance by an attractive surface (NGF)
Growth cone guidance by an adhesive substrate
Growth cone guidance by a repellent surface (ephrinA2)
Activation of ADF(cofilin) mediates attractive growth cone guidance
| Attachment | Size |
|---|---|
| Teacher Guide | 82.68 KB |
| Teacher Guide in MS Word format | 224 KB |